Experts around the world – including NJ, NYC and the rest of the Tristate area – are choosing the Leksell Gamma Knife Icon system to treat. OBJECTIVE: The objective of this study is to introduce a new radiosurgical device , the Leksell Gamma Knife Perfexion (Elekta Instruments AB, Stockholm. A new model of Leksell Gamma Knife® (LGK), known as Perfexion™ (LGK PFX), was introduced by Elekta Instrument, AB, Sweden, in This model has a.

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Paddick I, Lippitz B. The Perfexion exceeds the capabilities of previous gamma knife models in terms of treatment efficiency, conformity, and radiation protection. Lindquist C, Paddick I. The system also provides more options to generate plan with high dosimetric conformity. Despite increasing the treatment range, the average source-to-focus distance is still kept very close to previous models due to an improved design of the collimator system of LGK PFX.

The Leksell Gamma Knife Perfexion and comparisons with its predecessors.

Footnotes Source of Support: Today, cranial radiosurgery with Perfexion is performed in hundreds of leading hospitals and clinics around the world. Author information Article notes Copyright and License information Disclaimer. Radiosurgery with the world’s first fully robotized Leksell Gamma Knife Perfexion in clinical use: Dose plans for the Leksell Gamma Knife Models B, 4C, and Perfexion have been created for target pathologies to illustrate how the software and hardware of the new radiosurgical system can increase treatment quality, decrease treatment time, and increase patient comfort.


These qualities enable treatment of larger target volumes, especially close to eloquent areas. The hardware for the imager was designed and built in-house at the Princess Margaret Hospital. Non-uniform output from the sectors will affect the isodose pattern during irradiation but such an effect will not be accounted for by the Leksell GammaPlan software, which assumes output from each sector to be uniform.

The LGK PFX demonstrated a high level efficiency in workflow thus reducing significantly the total treatment time especially for the treatment of multiple metastases. Flexible and intuitive workflows Well-defined workflows enable fast and intuitive dose planning, even for complex cases.

Twenty-one patients underwent radiosurgical treatment of multiple brain metastases using median 9 isocenters on LGK PFX. Gamma angles 72, lekse,l,for APS for patient’s head fixation. Performance-related features in the design of the new radiosurgical system are described, and the ability to create complex shapes of isodose volumes even with a single isocenter is demonstrated.

The Leksell Gamma Knife Perfexion and comparisons with its predecessors.

The manufacturer’s specification required initial output to be more than 3. No need for margins Planned dose equals delivered dose with guaranteed system accuracy over lifetime of device 1 prfexion with a Platinum service contract.

GI is calculated by. For the same reason, the number of patients scheduled for treatment on LGK PFX more than doubled the number of patients scheduled for treatment on the 4C unit.

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Equally high accuracy and ease of use for frame-based or frameless treatments, and for single or multiple targets. Coincidence of mechanical and dosimetric isocenter was evaluated by two diferent methods. C Sector position which defines a 4 mm collimator.


A comparison of the gamma knife model C and the automatic positioning system with Leksell model B. In order to remove this flaw, Paddick suggested an alternate quantity, known as PCI, with the following expression.

By continuing to browse the site you are agreeing to our use of cookies. Journal List J Med Phys v. Using these images, the treatment plan is developed. The sector movement is performed by servo-controlled motors with linear scales located at the perexion of the radiation unit. Today, cranial radiosurgery with Perfexion is performed knifee hundreds of leading hospitals and clinics around the world.

Leksell Gamma Knife® Icon™

Physical Aspects of Stereotactic Radiosurgery. Results for measured X, Y, Z profiles for 4, 8 and 16 mm collimators are given in Table 4. This article is also available for rental through DeepDyve.

This arrangement of sources differs substantially from the previous hemispherical arrangements of 60 Co sources in the U, B, C and 4C units and results in different source-to-focus distance for each ring perexion from mm to mm. Evidence-based performance Clinically proven, extensively published and expertly supported technology. Perfexion is a fully integrated system and complete solution. Total treatment time on the LGK PFX even for patients with very complex treatments brain tumors never exceeded two hours.

Ideal for stereotactic treatment gammma.