La lentiginosis unilateral parcial es un trastorno pigmentario poco común, caracterizado por la agrupación unilateral de numerosas manchas marrones que . Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal. Partial unilateral lentiginosis colocalized with naevus depigmentosus. S. I. In. Department of Dermatology, Ajou University School of Medicine.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, parcal, and reproduction in any medium, provided the original author and source are credited. There is a hypothesis that LUP may represent a mosaicism of a generalized form of lentiginosis with melanocytic proliferation likewise the LEOPARD syndromeforming real lentigos simplex and eventually may be subject to malignant transformation [ 2 ].

References Supplied oarcial CrossRef. Statement of Ethics Informed consent was obtained from the patient for being included in this case report.

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J Am AcadDermatol 8: These results revealed that low-fluence Lentigunosis Nd: It is unilateeal possible that the resulting metabolites from the arachidonic acid pathway and histamine from mast cells may affect melanogenesis [ 14 ], thus resulting in PIH.

Two Lisch nodules of the iris were recognized in the left eye but none in the right eye, which is why we established a diagnosis of segmental neurofibromatosis 1. Can’t read the image? Also, scarring, long downtime, and pain are important issues. Int J Dermatol Discrete fibroplasia, melanophages and sparse mononuclear inflammatory reaction are present in the papillary dermis. Introduction Partial unilateral lentiginosis PUL is a rare pigmentary disorder characterized by multiple lentigines grouped within an area of normal skin, often in a segmental pattern [ 1 ].


It is more common in white skin and rare in black skin. Discussion PUL have been reported under various names, including unilateral lentigines, lentiginous unipateral, segmental lentiginosis, larcial lentiginous naevus, and agminated lentiginosis [ 3 ].

It is characterized by multiple lentigines that are grouped in a segmental pattern with a sharp demarcation at the midline.

The patient was treated at 1-week intervals starting with a spot size of 6 mm, a fluence of 2. Partial unilateral lentiginosis, 1,nm Q-switched neodymium-doped yttrium aluminum garnet laser. Pxrcial using conventional laser methods are sometimes unsatisfactory due to common side effects, such as postinflammatory hyperpigmentation PIHscarring, and recurrences.

Melanocytic Nevi – Partial Unilateral Lentiginosis | Perri Dermatology

Before treatment aafter 4 treatment sessions before fluence elevation band 4 weeks after completion of laser treatment c. Select your language of interest to view the total content in your interested language. You can change the settings or obtain more information by clicking here. The basal layer is usually hyperpigmented and foci of melanic pigment can be found in the horny layer. The epidermal stem cell factor is over-expressed in lentigo senilis: Abnormal melanocytes are replaced by normal melanocytes which migrate from outer root sheath of hair [ 9101112 ].

Treatment is indicated for the improvement of the esthetic aspects of the patients. Open in a separate window. Habit-associated salivary pH changes in oral submucous fibrosis-A controlled cross-sectional study. Sign up for further access to Scientific Publications and Authors!

Previous article Next article. Although the exact mechanism by which low-fluence 1,nm QS Nd: Please do not submit any personal or private information unless you are comfortable doing so. PUL have been reported under various names, including unilateral lentigines, lentiginous mosaicism, segmental lentiginosis, zosteriform lentiginous naevus, and agminated lentiginosis [ 3 ].

Lentiginosis unilateral parcial. | Actas Dermo-Sifiliográficas (English Edition)

Please understand that if you email us, you are agreeing to the use of an unsecured method and understand all replies will be sent in the same fashion and you are authorizing this. The treatment was well tolerated with no significant side effects, including purpura, PIH, or scarring, except for mild erythema and a transient burning sensation immediately pracial the laser treatment, which disappeared within 1 h.


Melanocytic cells, as the uilateral cells, have the same ectodermal origin. In Partial Unilateral Lentiginosis, small brown melanocytic nevi develop on one half of the body. Usage and distribution for commercial purposes requires written permission. Dermatology ; 4: Physical examination revealed multiple brown parcixl measuring 1. By checking this box you hereby agree to hold Perri Dermatology, its doctors and affiliates, harmless from any hacking or any other unauthorized use of your personal information by outside parties.

Conventional lasers may cause postinflammatory hyperpigmentation because keratinocytes are injured during the process. A low fluence Q-switched Nd: Moreover, the patient had a large speckled lentiginous nevus involving the left side of her trunk, and her father showed a similar skin disorder on his left buttock.

Melanocytic Nevi – Partial Unilateral Lentiginosis

Therefore, this result can also be interpreted as a selective photothermolytic effect of the laser on mature melanosomes. Case Report A year-old female presented with a history of unilateral hyperpigmented macules on her left cheek and periorbital area since early childhood. No claim or opinion on these pages is intended to be medical advice or to replace a one-on-one relationship with a qualified health care professional.